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Dear Listserve-


We wanted to say that we have had a good response to our announcement of this year's Carolina Workshop on Biosensors and Force Measurements in Living Cells thus far, but the good news is that there are still many spaces left.  It promises to be great weather, and awesome science, as usual.  Please tell a friend. The workshop is hosted by CISMM, our NIH/NIBIB resource (Center for Computer Integrated Systems for Microscopy and Manipulation).   To Register and for more information:  http://cismm.web.unc.edu/resources/events//<http://cismm.web.unc.edu/resources/events/>


A flyer that can be printed and put up near your lab is available at:

https://drive.google.com/file/d/1X3rm1wg63rfuk3QMiLV1HOG8Ss0tQCCI/view


Thanks!


Tim O'Brien


I reprint the announcement below:


The Tenth annual Carolina Workshop on Biosensors and Force Measurements in Living Cells is scheduled for May 15th – 18th, 2018.
Cells respond to external biochemical and mechanical cues to generate myriad responses including force generation, motility, gene expression and differentiation. The connection between external cue and internal response are the biochemical pathways that control the cell. Understanding these responses is critical to gaining insight into diverse biomedical phenomena such as cancer, immunity and tissue differentiation and morphogenesis. Our workshop will offer, through morning lectures and afternoon laboratory sessions, ways to assess the biochemistry and mechanobiology of cells, and the theoretical basis for interpreting physical properties, force sensing and force generation.  We will cover the use of FRET-based biosensors related to cell mechanics and responses, and the use of light-modulated signaling molecules. We will present the optics and plans for assembling your own versatile light control microscopy system that includes vertical light sheet microscopy, spinning total internal reflection fluorescence (TIRF) and photoactivation capability.  This year’s workshop will continue to include two morning sessions on image analysis using the FIJI toolbox, taught by guest speaker Teng-Leong Chew from HHMI Janelia Research Center. Experimental stations will include atomic force microscopy combined with light sheet microscopy, 3D force microscopy (magnetic tweezers), FRET microscopy using fluorescent biosensors and the production and use of traction force substrates with soft silicon gels that allow TIRF imaging.  This year our registration fee in only $300, and this includes all supplies, light breakfasts, and a conference dinner/poster session with Dr. Wes Legant as our Keynote Speaker.  The workshop is hosted by CISMM, our NIH/NIBIB resource (Center for Computer Integrated Systems for Microscopy and Manipulation).   To Register and for more information:  http://cismm.web.unc.edu/resources/events//<http://cismm.web.unc.edu/resources/events/>