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It's been a while since I used MetaMorph, so can't properly compare, but
we're happy with NIS-Elements here. Particularly multidimensional
visualisation is quick and easy to handle, and allows to produce movies
easily. Image processing is pretty potent as well, particularly
thresholding (adaptive etc) to quantify and make surface rendered models. I
also use macros, but mostly on the hardware/acquisition side. I wish it
would tie in better with ImageJ though, and/or have a light edition or
something more muscular than the viewer, so people can use it at home (for
weekend image analysis).
No commercial interest etc.

Philippe Laissue, PhD
University of Essex, Colchester CO4 3SQ, UK