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Kathy,
I recently improved section adhesion by using gelatin. These were 
paraffin sections but a similar technique may work for cryosections. Try 
coating your slides with a very dilute solution of plain gelatin 
although I do not know how that would affect an in-situ hybridization. 
For the paraffin sections I just sprinkled a little--0.5--1.0 cc of 
gelatin on the surface of the warm water bath I use for stretching the 
paraffin sections and picking them up on slides.

If you are well funded you may want to investigate a sophisticated 
system offered by Instrumedics.
www.instrumedics.com

-- 
Larry Ackerman
Hilary Beggs Laboratory
UCSF, Department of Ophthalmology
10 Koret Way, Room K130, Box 0730
San Francisco, CA, 94143

Lab 415-476-1081 Cell 415-999-4758 FAX 415-476-0336
Web Site: http://www.ucsf.edu/beggs/