> we want to measure changes of the chloride concentration in intact
> nerve cells. Does anyone know about a chloride-sensitive
> fluorescence dye that works with an Ar/Kr laser?

I had the same problem some time ago... the only Cl- sensitive probes
I know of are of the SPQ/MQAE type. There have been attempts to
synthesize Cl- probes that can be used in the visible light range
(e.g., with an Kr/Ar laser), but (if I remember correctly) they
seemed to be rather unstable and unsuitable for biological
applications.

Peter

____________________________________________________________________
Peter H.M. Klaren                    email: [log in to unmask]
Department of Biomedical Science     phone: +44 114 222 2328
University of Sheffield                fax: +44 114 276 5413
Western Bank
Sheffield S10 2TN
England