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I’m happy to share an opening in my group for a PhD-level scientific researcher at Genentech. Come develop and apply new microscopy-based technology to enable drug discovery! This is an opportunity to work with an amazing group of people who are inspired to make a positive impact in patients' lives. If you know anyone who might be a good fit, please encourage them to apply at the link below or to reach out to me directly.

https://careers.gene.com/us/en/job/GENEUS202204115002EXTERNALENUS/Principal-Scientific-Researcher


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THE POSITION
Principal Scientific Researcher, Cell and Tissue Genomics – Computational Microscopy


The Department of Cell and Tissue Genomics (CTG) within Genentech Research and Early
Development is seeking a highly talented and motivated Principal Scientific Researcher (PSR) to
develop and apply high-content microscopy methods to visualize and understand human disease. The
primary focus of this position will be on the hands-on integration of computational approaches to
assay development, instrumentation, and analysis methods to enable cutting-edge imaging
technologies that lead to clinically actionable insight. These efforts will span therapeutic areas,
including neuroscience, immunology, molecular oncology, and cancer immunology.
Responsibilities:
● Design and carry out assays for multiplexed spatial readouts of proteins, nucleic acids, and
other biomolecules.
● Implement and operate flexible, multimodal, fluorescence imaging systems capable of high
throughput imaging.
● Contribute to robust image processing and analysis workflows for large high-dimensional
datasets.
● Troubleshoot and find solutions to experimental roadblocks that arise during sample
preparation, imaging, and data analysis.
● Collaborate with cross-functional teams across the department as well as therapeutic areas,
pathology, and bioinformatics to design, execute, and analyze complex experiments and
generate hypotheses on mechanisms of disease progression and molecule response.
Qualifications:
● Doctorate degree in biology, biophysics, bioengineering or related field. Post-doctoral or
previous industry experience is desirable.
● Strong publication record of biological discovery and/or method development.
● Strong experience and expertise in cutting-edge fluorescence microscopy techniques.
Expertise in high-throughput assay development, multiplexed spatial methods and/or
single-molecule imaging is a plus. Experience building and/or working with custom build
microscopy systems is a plus.
● Experience in image processing and analysis. Experience in a scientific programming
language such as python or Matlab is preferred.
● Excellent communication, organizational, and collaboration skill sets along with
demonstrated creative problem-solving abilities.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

Genentech requires all new hires to be fully vaccinated against COVID-19 as of their start date. This requirement is a condition of employment at Genentech, and it applies regardless of whether the position is located at a Genentech campus or is fully remote.  If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited as a result of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.