Search the CONFOCAL archive at
http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal

In 2003 Brad Amos and John White wrote a review for the Journal of Biology of the Cell entitled "How the Confocal Laser Scanning Microscope. entered Biological Research" that covers the history of the MRC500 development and timeline of other confocal developments. This is freely available at:

www.biolcell.org/boc/095/0335/boc0950335.pdf

In this review they state that one of the first public showings of their prototype was at
the Symposium of the International Society for Analytical Cytology in Cambridge, UK, in 1987. 


Kevin W. Eliceiri
Director
Laboratory for Optical and Computational Instrumentation
http://www.loci.wisc.edu
Room 271 Animal Sciences
1675 Observatory Drive
Madison, WI 53706
Phone: 608-263-6288
Fax: 608-262-4570

----- Original Message -----
From: Patrick Van Oostveldt <[log in to unmask]>
Date: Wednesday, November 7, 2007 11:50 am
Subject: Re: First commercial single point confocal
To: [log in to unmask]

> Search the CONFOCAL archive at
> http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal
> 
> Dear,
> 
> As far as my memory is correct we recieved the first commercial MRC500 
>  
> confocal in Europe. Feb 1988. At that time some prototypes of Leica  
> were also displayed in EMBL. The EMBL system even had no possibility  
> 
> to use conventional object observation and hence you needed a rather  
> 
> blind imaging. Quite difficult if you have to look and search your  
> object with alone confocal illumination and slowscanning.
> Andrew Dixon, was than the most important person at BIORAD, probably  
> 
> he has some  exact dates.
> 
> As they told me the MRC500 was presented to the public in dec 1987 at  
> 
> the american cell biology meeting.
> Am I correct?
> 
> Patrick
> 
> Quoting "Wiegraebe, Winfried" <[log in to unmask]>:
> 
> > Search the CONFOCAL archive at
> > http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal
> >
> > How do the Zeiss laser scanning and confocal microscopes fit into this
> > history?
> > According to their web-page they had 1982 the first commercial laser
> > scanning microscope (not confocal), the LSM 44 and 1988 a confocal
> > system (the LSM 10).
> > Winfried
> >
> > ------------------------------------------------------------------------
> > --
> > Winfried Wiegraebe, Ph.D.
> > Dir. of Advanced Instrumentation & Physics
> > Stowers Institute for Medical Research
> > 1000 E. 50th St, Rm 454b
> > Kansas City, MO 64110
> > USA
> >
> > Phone: (816) 926-4415
> > Cell:     (816) 824-0287
> > Fax:     (816) 926-2088
> > Email:  [log in to unmask]
> > Web:    www.stowers-institute.org
> > http://research.stowers-institute.org/wiw/
> >
> >
> >
> 
> 
> 
> -- 
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