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Hi Sarah,

I successfully set-up a Patch clamp/ Laser scanning confocal system when I
was a professor at UCSD. We had an EPC-9 for single-channel and whole cell
patch recording in combination with a scanning confocal using a 100 mW Ar/Kr
laser. The laser and power supply were physically and electrically isolated
from the recording site on the confocal. We routinely performed a
combination of patch rcording along with confocal imaging.

Good luck!

Greg Maguire, Ph.D.

----- Original Message -----
From: "Locknar, Sarah A" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Wednesday, July 28, 2004 6:14 AM
Subject: Laser and electrophysiology


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Hi-
Not really a confocal question, but here goes:
I'm upgrading our confocal so I'm thinking about rearranging the room
while everything is down.  I came up with a new arrangement but wanted
some advice because the new scheme would position the laser (Melles
Griot Omnichrome Ar/Kr) next to our electrophysiology equipment.  Would
the laser power supply interfere with electrical recordings in any way?
Anyone with insight into possible noise problems should contact me
directly.  I only have a week to make up my mind about this so please
let me know ASAP!
Thanks-
Sarah

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Sarah Locknar, Ph.D.
Director, Neuroscience COBRE Imaging / Physiology Core
College of Medicine, University of Vermont
E015 Given Building
89 Beaumont Ave.
Burlington, VT 05405
802-656-0413
802-656-8704 (fax)
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