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October 2014

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Confocal Microscopy List <[log in to unmask]>
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Sun, 12 Oct 2014 17:44:43 +0800
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*****
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Post images on http://www.imgur.com and include the link in your posting.
*****

I fully agree with Prof. Guy Cox. We sincerely congratulate all the three
winners, because we all know that they well deserve it. And, this will
bring all of us a brighter future, because microscopy gets back to people's
vision. However, if being interpreted wrongly, the only-3-winner policy may
become a source of internal conflict, which hurts the community at large.
Let me share an old Chinese historic story: "Two peaches kill three
warriors".
----
 It was 2000BC in ancient China, there are three warriors who are great
generals during the war time. In peace time however, they respect nobody
because of their great contributions to the kingdom. So the king was
worried, and he consulted his senate. The senate said: "You can award them
with two best peaches of our country." So the king followed his suggestion,
saying that he will give the award to those with greatest contribution.

So the three warriers were invited to the ceremony. The first warrior
Gongsun, a very quick tempered person, responded:"I had killed one giant
tiger to save the king's life, I should deserve one." So he took one peach.
The second warrior Gu said:"A true warrior shows his power at war. I have
killed many enemies and won many hard battles, I am sure to have the right
of winning a peach as award." So he also took one.

The third warrior Tian was surprised at this fact. He didn't speak earlier
because he want to show some respect to his fellows, but the result is very
unacceptable to him. So he said, " You mentioned killing tiger and killing
people. Think about my deeds. Once our king is traveling across the Yellow
River, then a dragon jumps out of water and swallowed the lovely son of the
king. I fought with the monster for several hours, slaughter its head, and
saved the princess. Yet, I do not have any award. Enjoy the peach,
gentlemen!" After saying this, he took out his sward, and suicided.

Seeing the blood of Tian, Gongsun started to think: "Surely my contribution
is great, but comparing with Tian, it is nothing. Yet I see only the award,
and ignores my friends, this simply reflects my blindness and selfishness
in my character, which is completely unacceptable for a warrior." Thinking
that this kills his best friend, he took out his sward and cut his belly
also.
Then Gu cried: "We three had fought so many battles together, and already
swored to be brothers of different family name. We sowred to live and to
die together. Yet now, I flatter myself to compete with your contributions,
this is no rightousness; I am still alive while you both are dead, this is
no faith; I dare not to kill myself, this is no courage. I see no point
that I as a warrior should live like this. " So, he ended his life as well.

The senate won his trick, with two intact peaches.
-----

I wish that this ancient wisdom may bring more unity and harmony for our
community.  Only by united can our community get the full blessings from
super-resolution microscopy wining Nobel prize.
You can check out the story by yourself with help of google translate
through:   http://baike.baidu.com/view/44773.htm         By no means should
one connect the names and award to anybody or any organization in real life
in any form.

      Peng


Sincerely,
Peng Xi
Ph. D.    Associate Professor
Dept. of Biomedical Engineering, College of Engineering
Peking University, Beijing, China
Tel: +86 10-6276 7155
Email: [log in to unmask]
http://bme.pku.edu.cn/~xipeng/

On Fri, Oct 10, 2014 at 8:31 PM, Guy Cox <[log in to unmask]> wrote:

> *****
> To join, leave or search the confocal microscopy listserv, go to:
> http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
> Post images on http://www.imgur.com and include the link in your posting.
> *****
>
> Can I please make it clear that neither I, nor Nuno, nor other
> contributors who have mentioned other people, grudge these awards in the
> slightest.  The three winners (and I have known Stefan Hell for 30 years)
> all totally deserve their awards.  What's more, it is a boost for all of us
> that super-resolution microscopy has made the Nobel.  But as with many
> other cases in the past, the strait-jacket of only 3 winners (max) means
> that other deserving people miss out.  This is particularly the case where
> two topics share the same prize.  (cf EM and STM some years ago).  So,
> while congratulating the three winners, it is good that we recall other
> contributors, so that they will know that even if they didn't get the
> prize, they are still remembered by the community.
>
>                                                   Guy
>
> Guy Cox, Honorary Associate Professor
> School of Medical Sciences
>
> Australian Centre for Microscopy and Microanalysis,
> Madsen, F09, University of Sydney, NSW 2006
>
> -----Original Message-----
> From: Confocal Microscopy List [mailto:[log in to unmask]]
> On Behalf Of Andreas Schönle
> Sent: Friday, 10 October 2014 7:25 PM
> To: [log in to unmask]
> Subject: Re: congratulations to Eric, Stefan and W.E. for Nobel Prize in
> Chemistry, for the development of super-resolved fluorescence microscopy
>
> *****
> To join, leave or search the confocal microscopy listserv, go to:
> http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
> Post images on http://www.imgur.com and include the link in your posting.
> *****
>
> Dear Guy, Nuno, dear list members!
>
> Surely this discussion will now go on for a while but I would like to set
> a few facts straight, so it can be put on solid ground.
>
> 1)
> Stefan Hell was never a student of Chirstoph Cremer. His PhD advisor was
> Prof. S. Hunklinger and both 4pi and STED microscopy were conceived by him
> independently. The principle of STED is completely unrelated to 4pi and 4pi
> has nothing to do with what the Nobel prize was awarded for (see below).
> 2)
> 4pi microscopy is not a super-resolution method (it is diffraction
> limited).
> Christoph Cremer's original proposal to use light coming from all
> directions was aimed at increasing lateral resolution and was based on the
> wrong assumption that inverting the light-field of a point source <<lambda
> by means of a hologram could beat the diffraction limit.
> (this neglects the fact that the near field decays exponentially and that
> this cannot be inverted in conventional materials)
> 3)
> Localization is not resolution. Impressive work was done localizing single
> or several light sources separable by spectral properties, stepwise
> bleaching etc. - usually with the goal of measuring distances. But dense
> images can (as of now) only be obtained by time-sequentially switching
> molecules on and off.
> This was first realized for ensembles in STED and molecule-by-molecule in
> PALM/STORM/FPALM.
>
> Again, this is not to diminish anybody's work in the field. Over the years
> I have read many articles describing important and inspiring work. And I
> wholeheartedly agree that the field would not be where it is without these
> contributions.
> But when discussing who should be honored for finding the key to
> circumvent the diffraction limit in optical imaging, it is important to
> identify those people that had the right idea, recognized its importance
> and proved this by actually putting it to work.
>
> Best regards,
> Andreas
>
> --
> Andreas Schoenle, Dr.
> Abberior Instruments GmbH, D-37077 Goettingen, Germany
>
> phone: +49 (551) 30724170
> fax: +49 (551) 30724171
> http://www.abberior-instruments.com
> mailto:[log in to unmask]
>
> -----Original Message-----
> From: Confocal Microscopy List [mailto:[log in to unmask]]
> On Behalf Of Nuno Moreno
> Sent: Freitag, 10. Oktober 2014 00:19
> To: [log in to unmask]
> Subject: Re: congratulations to Eric, Stefan and W . E. for Nob el P rize
> in Chemistry, ³ for t he development of super-reso lved fluores cenc e mi
> croscopy²
>
> *****
> To join, leave or search the confocal microscopy listserv, go to:
> http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
> Post images on http://www.imgur.com and include the link in your posting.
> *****
>
> Dear Guy
>
> You're absolutely right. I actually sent an internal email (for the
> institute) a few hours after the announcement with, among other stuff,
> this:
>
> "As always there are many others that should be on the laureates list but
> one needed the final click. In my opinion Cremer from Heidelberg university
> should be one of them ...."
>
> Nuno Moreno
>
>
>
>
>
> On 09 Oct 2014, at 02:16, Guy Cox <[log in to unmask]> wrote:
>
> > *****
> > To join, leave or search the confocal microscopy listserv, go to:
> > http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
> > Post images on http://www.imgur.com and include the link in your
> posting.
> > *****
> >
> > The three names is always a problem - especially when the prize is
> > awarded
> essentially for two different techniques.  Christoph Cremer (Stefan's
> supervisor) could well also feel he'd been passed over.
> >
> >                                                            Guy
> >
>

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