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Why not Xiaowei Zhuang?


Sincerely,
Peng Xi
Ph. D.    Associate Professor
Dept. of Biomedical Engineering, College of Engineering
Peking University, Beijing, China
Tel: +86 10-6276 7155
Email: [log in to unmask]
http://bme.pku.edu.cn/~xipeng/

On Wed, Oct 8, 2014 at 7:51 AM, George McNamara <[log in to unmask]>
wrote:

> *****
> To join, leave or search the confocal microscopy listserv, go to:
> http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
> Post images on http://www.imgur.com and include the link in your posting.
> *****
>
> congratulations to Eric, Stefan and W.E. for Nobel Prize in Chemistry
>
> http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2014/press.html
>
>
>  Press Release
>
> 8 October 2014
>
> The Royal Swedish Academy of Sciences <http://www.nobelprize.org/
> redirect/links_out/prizeawarder.php?from=/nobel_
> prizes/chemistry/laureates/2014/press.html&object=kva&to=
> http://www.kva.se/en/> has decided to award the Nobel Prize in Chemistry
> for 2014 to
>
> *Eric Betzig*
> Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn,
> VA, USA,
>
> *Stefan W. Hell*
> Max Planck Institute for Biophysical Chemistry, Göttingen, and German
> Cancer Research Center, Heidelberg, Germany
>
> and
>
> *William E. Moerner*
> Stanford University, Stanford, CA, USA
>
> /“for the development of super-resolved fluorescence microscopy”/
>
>
>    Surpassing the limitations of the light microscope
>
> For a long time optical microscopy was held back by a presumed limitation:
> that it would never obtain a better resolution than half the wavelength of
> light. Helped by fluorescent molecules the Nobel Laureates in Chemistry
> 2014 ingeniously circumvented this limitation. Their ground-breaking work
> has brought optical microscopy into the nanodimension.
>
> In what has become known as nanoscopy, scientists visualize the pathways
> of individual molecules inside living cells. They can see how molecules
> create synapses between nerve cells in the brain; they can track proteins
> involved in Parkinson’s, Alzheimer’s and Huntington’s diseases as they
> aggregate; they follow individual proteins in fertilized eggs as these
> divide into embryos.
>
> It was all but obvious that scientists should ever be able to study living
> cells in the tiniest molecular detail. In 1873, the microscopist Ernst Abbe
> stipulated a physical limit for the maximum resolution of traditional
> optical microscopy: it could never become better than 0.2 micrometres.
> *Eric Betzig*, *Stefan W. Hell* and *William E. Moerner* are awarded the
> Nobel Prize in Chemistry 2014 for having bypassed this limit. Due to their
> achievements the optical microscope can now peer into the nanoworld.
>
> Two separate principles are rewarded. One enables the method /stimulated
> emission depletion (STED) microscopy/, developed by Stefan Hell in 2000.
> Two laser beams are utilized; one stimulates fluorescent molecules to glow,
> another cancels out all fluorescence except for that in a nanometre-sized
> volume. Scanning over the sample, nanometre for nanometre, yields an image
> with a resolution better than Abbe’s stipulated limit.
>
> Eric Betzig and William Moerner, working separately, laid the foundation
> for the second method, /single-molecule microscopy/. The method relies upon
> the possibility to turn the fluorescence of individual molecules on and
> off. Scientists image the same area multiple times, letting just a few
> interspersed molecules glow each time. Superimposing these images yields a
> dense super-image resolved at the nanolevel. In 2006 Eric Betzig utilized
> this method for the first time.
>
> Today, nanoscopy is used world-wide and new knowledge of greatest benefit
> to mankind is produced on a daily basis.
>
>
> //
>
> My thanks to the Nobel committee for revealing what W.E. is.
>
> --
>
>
>
> George McNamara, Ph.D.
> Single Cells Analyst
> L.J.N. Cooper Lab
> University of Texas M.D. Anderson Cancer Center
> Houston, TX 77054
> Tattletales http://works.bepress.com/gmcnamara/42
>