Regarding possible endogenous ligands for streptavidin, there was a report
in 1994 (or 93) that streptavidin bound to integrins. Perhaps that could
account for some "non-specific" labelling with biotin/avidin techniques.
Margaret Fransen, Ph.D.
Dept. of Anatomy & Cell Biology
SUNY Health Science Center @ Syracuse
750 E. Adams St. Syracuse NY 13210
Tel: 315 464 8525
Fax: 315 464 8535
E-mail: [log in to unmask]